Drug-Induced Skin Disease

Cover of: Drug-Induced Skin Disease |

Published by Informa Healthcare .

Written in English

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Subjects:

  • Dermatology,
  • Medical / Dermatology,
  • Medical,
  • Medical / Nursing

Edition Notes

Book details

ContributionsRebecca Gruchalla (Editor), Neil Shear (Editor)
The Physical Object
FormatHardcover
Number of Pages600
ID Numbers
Open LibraryOL11431874M
ISBN 100824754220
ISBN 109780824754228
OCLC/WorldCa144547786

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Drug-Induced Acne (Acneiform Eruption): Drug-induced acne accounts for approximately 1% of drug-induced skin reactions. 5 Pustular eruptions are typically observed on the face and upper trunk. 5,6 Comedones are not commonly documented with this type of outbreak. The eruption occurs 1 to 3 weeks after the causative agent is initiated.

According to the authors, a drug-induced disease as an unintended effect of a drug, which results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical attention and/or require hospitalization.

Since the first edition of this book was published innumerous drugs have been withdrawn from the market in the 5/5(1). Protect Your Patients: A Definitive Guide to Drug-Induced Disease.

Now in its third edition, this comprehensive guide provides a detailed overview of diseases that result from drug therapy, arming healthcare professionals with critical knowledge to protect the health and welfare of their patients.

Drug-induced Drug-Induced Skin Disease book disease. Kaplan AP. Drug-induced cutaneous reactions encompass a wide variety of rashes that depend in part on route of administration (e.g., contact versus systemic) as well as type of cutaneous response and molecular mechanism underlying the reaction.

One such reaction is a type IV immunologic reaction (delayed Cited by:   Drug induced skin disorders is defined as any skin disorders caused by a drug or medication.

It is estimated that 2—3 percent of hospitalised patients are affected by a drug eruption, and that serious drug eruptions occur in around 1 in patients. Drug-Induced Liver Disease, 3 rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more.

Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the. Since the first edition of this book was published innumerous drugs have been withdrawn from the market in the United States as a result of morbidity and/or mortality associated with drug-induced diseases.

Despite best efforts to assure that all drugs are safe and effective, millions of patients each year develop drug-induced diseases. Common Skin Diseases. This book consists of a core module and five satellite modules.

The Core Module is prepared for health officers, pubic health nurses, environmental health, medical laboratory technology students and Health extension Workers. Satellite modules are prepared to strengthen the professional training of each category. However, the changes of drug-induced skin disease must be made considering clinical presentation, histopathological analysis, and course of the disease.

PMID: [PubMed - indexed for MEDLINE] Publication Types: Review; MeSH Terms. Drug Eruptions/pathology* Humans; Skin Diseases/chemically induced* Skin Diseases/pathology*Cited by: PDF | On Dec 1,D Jullien and others published [Drug-induced skin diseases.

Diagnosis] | Find, read and cite all the research you need on ResearchGate. Drug-induced skin disease. Author links open overlay panel Allen P. Kaplan M.D. Show more. The major causes of drug-induced urticaria and an- gioedema are penicillin and related compounds, sulfa drugs, barbiturates (particularly phenobarbital).anti- convulsants, salicylates, foreign antisera.

allergy ex- tracts, radiocontrast materials, and Cited by:   According to the authors, a drug-induced disease as an unintended effect of a drug, which results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical attention and/or require hospitalization.

Since the first edition of this book was published innumerous Book Edition: Second Drug-Induced Skin Disease book. According to the authors, a drug-induced disease as an unintended effect of a drug, which results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical attention and/or require hospitalization.

Since the first edition of this book was published innumerous drugs have been withdrawn from the market in the United States as a result of morbidity and/or 5/5(1).

Drug-induced cutaneous rashes, whether confined to the skin or part of a systemic disease, are characterised by a spectrum of inflammatory disease patterns that include perivascular dermatitis.

The usual histologic patterns of drug eruptions are discussed in this review using the basic patterns of inflammatory diseases. Clinicopathologic correlation is established for relevant patterns. However, the changes of drug-induced skin disease must be made considering clinical presentation, histopathological analysis, and course of the disease.

Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the pharmaceutical.

Drug-induced liver disease (DILD) can have many different clinical presentations: idiosyncratic reactions, allergic hepatitis, toxic hepatitis, chronic active toxic hepatitis, toxic cirrhosis, and liver vascular disorders.

The mechanisms of DILD are diverse, representing many phases of biotransformation, and are susceptible to genetic polymorphism. is a rapid access, point-of-care medical reference for primary care and emergency clinicians.

Started inthis collection now contains interlinked topic pages divided into a tree of 31 specialty books and chapters. Drug eruptions are among the most common adverse drug reactions, affecting approximately 3% of hospitalised patients. Although the rate of severe cutaneous adverse reactions to medications is low, these reactions can affect anyone who takes medication, and can result in death or disability.

Two general patterns can be distinguished, depending on the type of onset of these Cited by: Drug-induced chronic cutaneous LE is the rarest of the three forms. It appears on average, eight months after starting the trigger medication.

Males and females have been equally affected, and the mean age of onset has been 59 years. Lesions resembling discoid lupus erythematosus (DLE) have been the most common presentation, but LE tumidus has.

Drug-Induced Pemphigus; Dry Skin; Wet Dressings These images are a random sampling from a Bing search on the term "Drug-induced Photosensitivity." Book Geriatric Medicine Book Gynecology Book Hematology and Oncology Book Human Immunodeficiency Virus Book Infectious Disease Book Jokes Book Mental Health Book Neonatology Book Nephrology.

The skin eruption should be carefully assessed to help distinguish between a disease condition and a drug-induced skin reaction. Drug-induced skin reactions can be irritant or allergic in nature. Allergic drug reactions can be classified into exanthematous, urticarial, blistering, and pustular eruptions.

ADRs can cause serious harm to the patient, as well as carrying medico-legal and economic consequences. Fortunately, only about 2% of all drug-induced skin reactions are severe and very few are fatal. However, all drug-induced skin eruptions can cause morbidity, affect the patient’s confidence in the prescriber and future adherence with.

A risk factor for drug-induced skin disease identified Date: December 7, Source: Hokkaido University Summary: Researchers have identified a type of.

Bullous drug eruptions (immunobullous disease is important to recognise, as drug withdrawal leads to clearance) Drug-induced lupus erythematosus. A drug eruption is sometimes, unnecessarily, called a cutaneous drug eruption. Drugs can also cause: Drug-induced skin pigmentation.

Drug-induced liver disease comes in many types, and has many potential causes. Find out about drug-induced liver disease treatment, signs, and symptoms like itching, easy bruising, and jaundice, and learn how certain drugs can cause liver : Dennis Lee, MD.

Drug induced dyskinesia is an involuntary movement disorder. Signs and symptoms include repetitive and irregular motions of the mouth, face, limbs and/or trunk. Treatment with antipsychotic drugs and levodopa (commonly used to treat Parkinson disease) are well recognized causes of drug-induced dyskinesia.

Dyskinesia develops in around 40% of people with Parkinson's. Abstract and Introduction Acute Drug-induced Skin Disorders Chronic Drug-induced Skin Disorders Conclusion References Warfarin tissue necrosis is a.

Autoimmune disease involving musculoskeletal, skin, kidneys and CNS Epidemiology • 15KK cases / year • K people have drug induced SLE in US • % of cases of SLE are drug induced Mechanism • Alterations in immunologic pathways or drug metabolism • Molecular mimecry – Rx like a nucleic acid (hydralazine – adenosine)File Size: KB.

drug-induced disease: a toxic reaction to or morbid condition resulting from the administration of a drug. A risk factor for drug-induced skin disease identified by Hokkaido University Non-inflammatory bullous pemphigoid (BP) seen in the type 2 diabetes patient.

The skin is the largest organ in the body and is continually exposed to external stimuli, such as chemical and environmental substances. Cutaneous toxicity can be broadly classified according to the mechanism of onset, namely: contact dermatitis, i.e., damage resulting from contact with a substance (irritant dermatitis, allergic contact dermatitis, chemical burns); photosensitivity, i.e Cited by: 1.

Drug-induced pigmentation represents 10 to 20% of all cases of acquired hyperpigmentation and this hypothesis must be systematically raised in unexplained pigmented lesions especially in elderly people. The pathogenesis of drug-induced pigmentation is variable according to the causative medication and can involve an accumulation of melanin, sometimes following a nonspecific Cited by:   T1 - Drug-Induced Acneiform Eruptions.

T2 - Drug-induced Acneiform Eruptions. AU - Do, Ha K. AU - Ezra, Navid. AU - Wolverton, Stephen. PY - /1/1. Y1 - /1/1. N2 - Acne vulgaris is a polymorphic infl ammatory skin disease, clinically characterized by mixture of comedones, superficial and deep infl amed papules, pustules, and : Ha K.

Do, Navid Ezra, Stephen E. Wolverton. Since the first edition of this book was published innumerous drugs have been withdrawn from the market in the United States as a result of morbidity and/or mortality associated with drug-induced diseases. Despite best efforts to assure that all drugs are safe and effective, millions of patients each year develop drug-induced diseases.5/5(3).

Pemphigus (/ ˈ p ɛ m f ɪ ɡ ə s / or / p ɛ m ˈ f aɪ ɡ ə s /) is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. The name is derived from the Greek root "pemphix," meaning "pustule." In pemphigus, autoantibodies form against lein forms the "glue" that attaches adjacent epidermal cells via attachment points called lty: Dermatology.

Published in in the journal Clinical Pharmacology & Therapeutics in an article by researchers from the University of Toronto, and now in the public domain, the Naranjo scale is an underutilized tool for determining whether disease symptoms are caused by drugs, according to authors of a recent manual on drug-induced disease published by the.

—CNS: CNS involvement is very rare in drug-induced lupus. There are few reports of neuropathy. —Skin: Lupus skin findings (e.g., malar rash, oral ulcers, photosensitivity, vasculitic skin lesions) are uncommon in most patients with drug-induced lupus, with the notable exception of.

Drug-induced pulmonary disease is lung disease brought on by a bad reaction to a medicine. Causes. Many types of lung injury can result from medicines. It is usually impossible to predict who will develop lung disease from a medicine.

Types of lung problems or. Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs.

DPP-4 inhibitor (DPP-4i) is widely used to treat type 2 diabetes, but increased cases of bullous pemphigoid (BP) have been reported among patients. Drug-induced pigmentation of the skin may occur as a consequence of drug administration, and the mechanism may be postinflammatory hyperpigmentation in some cases, but frequently is related to actual deposition of the offending drug in the skin.: –6 The incidence of this change varies, and depends on the type of medication involved.Drug-induced lupus erythematosus is similar but not identical to systemic lupus erythematosus (SLE).

It is an autoimmune disorder. This means your body attacks healthy tissue by mistake. It is caused by a reaction to a medicine. Related conditions are drug-induced cutaneous lupus and .Researchers have identified a type of human leukocyte antigen that is associated with the skin disease bullous pemphigoid.

Researchers identify risk factor for drug-induced skin disease Become a member.

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